1,1'-Biphenyl, 4-(bromomethyl)- → [4-(Biphenyl-4-ylmethylsulfanyl)-2-methyl-phenoxy]-acetic acid

HRID 1063656Notes

Reaction equation

HRID 1063656 reaction equation
C[O:2][C:3](=[O:14])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([SH:12])=[CH:8][C:7]=1[CH3:13].Br[CH2:16][C:17]1[CH:22]=[CH:21][C:20]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[CH:19][CH:18]=1>>[C:20]1([C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH:19]=[CH:18][C:17]([CH2:16][S:12][C:9]2[CH:10]=[CH:11][C:6]([O:5][CH2:4][C:3]([OH:2])=[O:14])=[C:7]([CH3:13])[CH:8]=2)=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 2577161,1'-Biphenyl, 4-(bromomethyl)-HCID 20770797Methyl (2-methyl-4-sulfanylphenoxy)acetate

Product 1

HCID 22280164[4-(Biphenyl-4-ylmethylsulfanyl)-2-methyl-phenoxy]-acetic acid

Procedure

The title compound was prepared in the manner analogous to Example 1F using 2C and 1E. MS m/z 379 (M+1).

Sources & evidence

ORD record
ord-6457104cfc1f413a8f8e89ec569e0549
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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