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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063659Generated: November 2, 2026

(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl Ester → [5-Methoxy-2-methyl-4-(4'-trifluoromethyl-biphenyl-4-ylmethylsulfanyl)-phenoxy]-acetic acid

https://huagongshe.com/reaction/1063659

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl EsterHCID 11311052—
Reactant4-(4-Trifluoromethylphenyl)benzylchlorideHCID 11459921—
Product[5-Methoxy-2-methyl-4-(4'-trifluoromethyl-biphenyl-4-ylmethylsulfanyl)-phenoxy]-acetic acidHCID 9825600—

Reaction Steps

The title compound was prepared in the manner analogous to Example 1F using 1D and 3B. MS m/z 477 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-6313d2bac00b4daba713f5e42d0e1b2b
Source noteuspto-grants-2005_11