Methyl (2-methyl-4-sulfanylphenoxy)acetate → [4-(4'-Chloro-3'-trifluoromethyl-biphenyl-4-ylmethylsulfanyl)-2-methyl-phenoxy]-acetic acid

HRID 1063663Notes

Reaction equation

HRID 1063663 reaction equation
C[O:2][C:3](=[O:14])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([SH:12])=[CH:8][C:7]=1[CH3:13].[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C:22]2[CH:27]=[CH:26][C:25]([CH2:28]Cl)=[CH:24][CH:23]=2)=[CH:18][C:17]=1[C:30]([F:33])([F:32])[F:31]>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C:22]2[CH:23]=[CH:24][C:25]([CH2:28][S:12][C:9]3[CH:10]=[CH:11][C:6]([O:5][CH2:4][C:3]([OH:2])=[O:14])=[C:7]([CH3:13])[CH:8]=3)=[CH:26][CH:27]=2)=[CH:18][C:17]=1[C:30]([F:31])([F:32])[F:33]

Participants

3

Reactant 2

HCID 20770797Methyl (2-methyl-4-sulfanylphenoxy)acetateHCID 222802044-Chloro-4'-chloromethyl-3-trifluoromethyl-biphenyl

Product 1

HCID 22280076[4-(4'-Chloro-3'-trifluoromethyl-biphenyl-4-ylmethylsulfanyl)-2-methyl-phenoxy]-acetic acid

Procedure

The title compound was prepared in the manner analogous to Example 1F using 2C and 6B. MS m/z 481 (M+1).

Sources & evidence

ORD record
ord-69b335d90d114b9fabc9649934c47628
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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