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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063667Generated: November 2, 2026

1-Bromo-3-(trifluoromethoxy)benzene → [5-Methoxy-2-methyl-4-(3'-trifluoromethoxy-biphenyl-4-ylmethylsulfanyl)-phenoxy]-acetic acid

https://huagongshe.com/reaction/1063667

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-(trifluoromethoxy)benzeneHCID 519964—
Reactant(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl EsterHCID 11311052—
Product[5-Methoxy-2-methyl-4-(3'-trifluoromethoxy-biphenyl-4-ylmethylsulfanyl)-phenoxy]-acetic acidHCID 22279994—

Reaction Steps

The title compound was prepared in the manner analogous to Example 5A using 1D and 1-bromo-3-trifluoromethoxy-benzene. MS m/z 493 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-a0be3c624b3b43c08423dc68b5b6e148
Source noteuspto-grants-2005_11