(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl Ester → {4-[5-(Trifluoromethyl)pyridin-2-yl]phenyl}methanol

HRID 1063672Notes

Reaction equation

HRID 1063672 reaction equation
C[O:2]C(=O)COC1C=C(OC)C(S)=CC=1C.Cl[CH2:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]2[CH:30]=[CH:29][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:27][N:26]=2)=[CH:21][CH:20]=1>>[F:32][C:31]([F:34])([F:33])[C:28]1[CH:29]=[CH:30][C:25]([C:22]2[CH:23]=[CH:24][C:19]([CH2:18][OH:2])=[CH:20][CH:21]=2)=[N:26][CH:27]=1

Participants

3

Reactant 2

HCID 11311052(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl EsterHCID 222800672-[4-(Chloromethyl)phenyl]-5-(trifluoromethyl)pyridine

Product 1

HCID 22280022{4-[5-(Trifluoromethyl)pyridin-2-yl]phenyl}methanol

Procedure

The title compound was prepared in the manner analogous to Example 1F using 1D and 18B. MS m/z 478 (M+1).

Sources & evidence

ORD record
ord-4409d35b14f54e3588d05ef2a58e810b
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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