4-[(4-Methoxyphenyl)methoxy]benzenemethanol → {4-[4-(4-Methoxy-benzyloxy)-benzylsulfanyl]-2-methyl-phenoxy}-acetic acid

HRID 1063683Notes

Reaction equation

HRID 1063683 reaction equation
COC1C=CC(COC2C=CC(CO)=CC=2)=CC=1.C[O:20][C:21](=[O:49])[CH2:22][O:23][C:24]1[CH:29]=[CH:28][C:27]([S:30][CH2:31][C:32]2[CH:37]=[CH:36][C:35]([O:38][CH2:39][C:40]3[CH:45]=[CH:44][C:43]([O:46][CH3:47])=[CH:42][CH:41]=3)=[CH:34][CH:33]=2)=[CH:26][C:25]=1[CH3:48]>>[CH3:47][O:46][C:43]1[CH:44]=[CH:45][C:40]([CH2:39][O:38][C:35]2[CH:36]=[CH:37][C:32]([CH2:31][S:30][C:27]3[CH:28]=[CH:29][C:24]([O:23][CH2:22][C:21]([OH:49])=[O:20])=[C:25]([CH3:48])[CH:26]=3)=[CH:33][CH:34]=2)=[CH:41][CH:42]=1

Participants

3

Reactant 2

HCID 126484214-[(4-Methoxyphenyl)methoxy]benzenemethanolHCID 20827029HCID 20827029, compound2×

Product 1

HCID 22280141{4-[4-(4-Methoxy-benzyloxy)-benzylsulfanyl]-2-methyl-phenoxy}-acetic acid

Procedure

The title compound was prepared in the manner analogous to Example 3B using 33A. MS m/z 227 (M-Cl). Step 3. Preparation of {4-[4-(4-Methoxy-benzyloxy)-benzylsulfanyl]-2-methyl-phenoxy}-acetic acid methyl ester (Compound 33C)

Sources & evidence

ORD record
ord-4c808ad935674d47b12db2d4874b8716
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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