(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl Ester → [5-Methoxy-2-methyl-4-(3-methyl-4'-trifluoromethyl-biphenyl-4-ylmethylsulfanyl)-phenoxy]-acetic acid

HRID 1063690Notes

Reaction equation

HRID 1063690 reaction equation
C[O:2][C:3](=[O:16])[CH2:4][O:5][C:6]1[CH:11]=[C:10]([O:12][CH3:13])[C:9]([SH:14])=[CH:8][C:7]=1[CH3:15].Cl[CH2:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]2[CH:30]=[CH:29][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:27][CH:26]=2)=[CH:21][C:20]=1[CH3:35]>>[CH3:13][O:12][C:10]1[C:9]([S:14][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]3[CH:30]=[CH:29][C:28]([C:31]([F:32])([F:33])[F:34])=[CH:27][CH:26]=3)=[CH:21][C:20]=2[CH3:35])=[CH:8][C:7]([CH3:15])=[C:6]([CH:11]=1)[O:5][CH2:4][C:3]([OH:2])=[O:16]

Participants

3

Reactant 2

HCID 11311052(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl EsterHCID 222801404-Chloromethyl-3-methyl-4'-trifluoromethyl-biphenyl

Product 1

HCID 10288768[5-Methoxy-2-methyl-4-(3-methyl-4'-trifluoromethyl-biphenyl-4-ylmethylsulfanyl)-phenoxy]-acetic acid

Procedure

The title compound was prepared in the manner analogous to Example 1F using 1D and 39B. MS m/z 491 (M+1).

Sources & evidence

ORD record
ord-a737880caa6a4a0ea73650be079c689f
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

Loading…