Methyl (2-methyl-4-sulfanylphenoxy)acetate → {2-Methyl-4-[5-(4-trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-phenoxy}-acetic acid

HRID 1063696Notes

Reaction equation

HRID 1063696 reaction equation
Cl[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=2)[O:5][N:4]=1.C[O:19][C:20](=[O:31])[CH2:21][O:22][C:23]1[CH:28]=[CH:27][C:26]([SH:29])=[CH:25][C:24]=1[CH3:30]>>[CH3:30][C:24]1[CH:25]=[C:26]([S:29][CH2:2][C:3]2[CH:7]=[C:6]([C:8]3[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=3)[O:5][N:4]=2)[CH:27]=[CH:28][C:23]=1[O:22][CH2:21][C:20]([OH:31])=[O:19]

Participants

3

Reactant 2

HCID 20770797Methyl (2-methyl-4-sulfanylphenoxy)acetateHCID 220642603-(Chloromethyl)-5-[4-(trifluoromethyl)phenyl]isoxazole

Product 1

HCID 22229314{2-Methyl-4-[5-(4-trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-phenoxy}-acetic acid

Procedure

The title compound was prepared in a manner analogous to Example 1F using 42C and 2C. MS m/z 438 (M+1).

Sources & evidence

ORD record
ord-2d88c669c9c04c59a2c1ca1605e1d54c
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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