1-(Chloromethyl)-4-phenoxybenzene → 2-Methyl-4-(4-phenoxy-benzylsulfanyl)-phenoxyl-acetic acid

HRID 1063699Notes

Reaction equation

HRID 1063699 reaction equation
Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:5][CH:4]=1.C[O:17][C:18](=[O:29])[CH2:19][O:20][C:21]1[CH:26]=[CH:25][C:24]([SH:27])=[CH:23][C:22]=1[CH3:28]>>[CH3:28][C:22]1[CH:23]=[C:24]([S:27][CH2:2][C:3]2[CH:8]=[CH:7][C:6]([O:9][C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[CH:5][CH:4]=2)[CH:25]=[CH:26][C:21]=1[O:20][CH2:19][C:18]([OH:29])=[O:17]

Participants

3

Reactant 2

HCID 5209941-(Chloromethyl)-4-phenoxybenzeneHCID 20770797Methyl (2-methyl-4-sulfanylphenoxy)acetate

Product 1

HCID 222800072-Methyl-4-(4-phenoxy-benzylsulfanyl)-phenoxyl-acetic acid

Procedure

The title compound was prepared in the manner analogous to Example 1F with 1-chloromethyl-4-phenoxy-benzene and 2C. MS m/z 321 (M-methylacetate).

Sources & evidence

ORD record
ord-8cee5cad7ded46e29fe8dcd55cf9b684
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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