(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl Ester → [5-Methoxy-2-methyl-4-(4'-trifluoromethyl-biphenyl-3-ylmethylsulfanyl)-phenoxy]-acetic acid

HRID 1063702Notes

Reaction equation

HRID 1063702 reaction equation
Cl[CH2:2][C:3]1[CH:4]=[C:5]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[CH:11][CH:10]=2)[CH:6]=[CH:7][CH:8]=1.C[O:20][C:21](=[O:34])[CH2:22][O:23][C:24]1[CH:29]=[C:28]([O:30][CH3:31])[C:27]([SH:32])=[CH:26][C:25]=1[CH3:33]>>[CH3:31][O:30][C:28]1[C:27]([S:32][CH2:2][C:3]2[CH:4]=[C:5]([C:9]3[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[CH:11][CH:10]=3)[CH:6]=[CH:7][CH:8]=2)=[CH:26][C:25]([CH3:33])=[C:24]([CH:29]=1)[O:23][CH2:22][C:21]([OH:34])=[O:20]

Participants

3

Reactant 2

HCID 11311052(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl EsterHCID 222801383-(4-Trifluoromethylphenyl)-benzyl chloride

Product 1

HCID 22280188[5-Methoxy-2-methyl-4-(4'-trifluoromethyl-biphenyl-3-ylmethylsulfanyl)-phenoxy]-acetic acid

Procedure

The title compound was prepared in the manner analogous to Example 1F using 48B and 1D. MS m/z 477 (M+1).

Sources & evidence

ORD record
ord-e1c8ff5cc7ae4c79b7b6c6809468eb2d
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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