{4-[(4-Fluorophenyl)methoxy]phenyl}methanol → HCID 22280142, compound

HRID 1063707Notes

Reaction equation

HRID 1063707 reaction equation
FC1C=CC(COC2C=CC(CO)=CC=2)=CC=1.C[O:19][C:20](=[O:47])[CH2:21][O:22][C:23]1[CH:28]=[CH:27][C:26]([S:29][CH2:30][C:31]2[CH:36]=[CH:35][C:34]([O:37][CH2:38][C:39]3[CH:44]=[CH:43][C:42]([F:45])=[CH:41][CH:40]=3)=[CH:33][CH:32]=2)=[CH:25][C:24]=1[CH3:46]>>[F:45][C:42]1[CH:41]=[CH:40][C:39]([CH2:38][O:37][C:34]2[CH:33]=[CH:32][C:31]([CH2:30][S:29][C:26]3[CH:27]=[CH:28][C:23]([O:22][CH2:21][C:20]([OH:47])=[O:19])=[C:24]([CH3:46])[CH:25]=3)=[CH:36][CH:35]=2)=[CH:44][CH:43]=1

Participants

3

Reactant 2

HCID 2737278{4-[(4-Fluorophenyl)methoxy]phenyl}methanolHCID 20827027HCID 20827027, compound2×

Product 1

HCID 22280142HCID 22280142, compound

Procedure

The title compound was prepared in the manner analogous to Example 3B using 57A. MS m/z 215 (M-Cl). Step 3. Preparation of {4-[4-(4-Fluoro-benzyloxy)-benzylsulfanyl]-2-methyl-phenoxy}-acetic acid methyl ester (Compound 57C)

Sources & evidence

ORD record
ord-7194dd3b37234868a8af783d756fc7ea
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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