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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063711Generated: November 3, 2026

4-Hydroxybenzyl Alcohol → {7-[4-(2,4-Dichloro-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acid

https://huagongshe.com/reaction/1063711

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxybenzyl AlcoholHCID 125—
Reactant2,4-Dichlorobenzyl chlorideHCID 7212—
Reactant(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl EsterHCID 20770872—
ReactantHCID 69470297HCID 69470297—
Reactant4-Chloromethyl-(4-trifluoromethyl-benzyloxy-benzene)HCID 69470598—
Product{7-[4-(2,4-Dichloro-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acidHCID 22280129—

Reaction Steps

The title compound was prepared in the manner analogous to Example 1F using 12C and 4-chloromethyl-(2,4-dichloro-benzyloxy-benzene) prepared from 4-hydroxymethyl-phenol and 1-chloromethyl-2,4-dichloro-benzene in the manner analagous to Examples 14A and 14B. MS m/z 503 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-a5a043b59f4e448f8f2c400ca418af5d
Source noteuspto-grants-2005_11