Potassium Bromide → {7-[4-(2,4-Dichloro-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acid

Participants

Role	Name	HCID	Charge
Reactant	Potassium Bromide	HCID 253877	—
Reactant	{7-[4-(2,4-Dichloro-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acid methyl ester	HCID 20827078	—
Product	{7-[4-(2,4-Dichloro-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acid	HCID 22280129	—

Reaction Steps

The title compound was prepared in the manner analogous to Example 1 using 62A. mp 149-150° C.; IR (KBr) cm−1: 3089, 1734, 1512, 1473, 1295, 1234; 400 MHz 1H NMR (DMSO-d6): δ 13.11 (br(s), 1H), 7.40-7.71 (m, 3H), 6.88-7.19 (m, 5H), 6.58 (d, 1H, J=8.5 Hz), 5.07 (s, 2H), 4.61 (s, 2H), 3.96 (s, 2H), 2.77 (t, 2H, t, J=7.4 Hz), 2.69 (t, 2H, J=7.4 Hz), 1.91 (pentet, 2H); MS m/z 487 (M−1). Anal. Calc'd for C25H22Cl2O4S: C, 61.35; H, 4.53. found: C, 60.95; H, 4.41.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06964983B2
Source dataset	uspto-grants-2005_11
ORD ID	ord-0ae3078dfc99479f944daae6720c6002
Source note	uspto-grants-2005_11