HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzyl Alcohol → {7-[4-(4-Methoxy-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzyl Alcohol | HCID 125 | — |
| Reactant | 4-Methoxybenzyl bromide | HCID 165021 | — |
| Reactant | (7-Mercapto-indan-4-yloxy)-acetic Acid Methyl Ester | HCID 20770872 | — |
| Reactant | 4-Chloromethyl-(4-methoxy-benzyloxy-benzene) | HCID 69467825 | — |
| Reactant | 4-Chloromethyl-(4-trifluoromethyl-benzyloxy-benzene) | HCID 69470598 | — |
| Product | {7-[4-(4-Methoxy-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic Acid | HCID 22280062 | — |
Reaction Steps
The title compound was prepared in the manner analogous to Example 1F using 12C and 4-chloromethyl-(4-methoxy-benzyloxy-benzene) prepared from 4-hydroxymethyl-phenol and 1-bromomethyl-4-methoxy-benzene in the manner analagous to Examples 14A and 14B. MS m/z 465 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06964983B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-0a5e9db8311f418fb5e88c35863532a2 |
| Source note | uspto-grants-2005_11 |