HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzyl Alcohol → {7-[4-(3,4-Dichloro-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzyl Alcohol | HCID 125 | — |
| Reactant | 4-(Bromomethyl)-1,2-dichlorobenzene | HCID 639726 | — |
| Reactant | (7-Mercapto-indan-4-yloxy)-acetic Acid Methyl Ester | HCID 20770872 | — |
| Reactant | HCID 22280207 | HCID 22280207 | — |
| Reactant | 4-Chloromethyl-(4-trifluoromethyl-benzyloxy-benzene) | HCID 69470598 | — |
| Product | {7-[4-(3,4-Dichloro-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic Acid | HCID 22280059 | — |
Reaction Steps
The title compound was prepared in the manner analogous to Example 1F using 12C and 1,2-Dichloro-4-(4-chloromethyl-phenoxymethyl)-benzene prepared from 1-bromomethyl-3,4-dichloro-benzene and 4-hydroxymethyl-phenol in the manner analagous to Examples 14A and 14B. MS m/z 503 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06964983B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-a7ba193a52a04c7ca356d9bf8ed958ec |
| Source note | uspto-grants-2005_11 |