HRID1063730

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID125

4-Hydroxybenzenemethanol

C7H8O2

HCID2737577

4-Fluoro-3-(trifluoromethyl)benzyl bromide

C8H5BrF4

HCID20770872

未命名化合物

HCID22280162

未命名化合物

HCID69470598

未命名化合物

PRODUCTS

生成物

结构：O=C(O)COc1ccc(SCc2ccc(OCc3ccc(F)c(C(F)(F)F)c3)cc2)c2c1CCC2

HCID22280122

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in the manner analogous to Example 1F using 12C and 4-(4-Chloromethyl-phenoxymethyl)-1-fluoro-2-trifluoromethyl-benzene prepared from 1-bromomethyl-4-fluoro-3-trifluoromethyl-benzene and 4-hydroxymethyl-phenol in the manner analagous to Examples 14A and 14B. MS m/z 283 (M−237).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-959b2c1816a54aea8b7924c2983bbeaf
来源数据集: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06964983B2
来源说明: uspto-grants-2005_11

反应 SMILES

C[O:2][C:3](=[O:16])[CH2:4][O:5][C:6]1[CH:14]=[CH:13][C:12]([SH:15])=[C:11]2[C:7]=1[CH2:8][CH2:9][CH2:10]2.Cl[CH2:18][C:19]1[CH:37]=[CH:36][C:22]([O:23][CH2:24][C:25]2[CH:30]=[CH:29][C:28]([F:31])=[C:27]([C:32]([F:35])([F:34])[F:33])[CH:26]=2)=[CH:21][CH:20]=1.BrCC1C=CC(F)=C(C(F)(F)F)C=1.OCC1C=CC(O)=CC=1.ClCC1(C(F)(F)F)C=CC(OCC2C=CC=CC=2)=CC1>>[F:31][C:28]1[CH:29]=[CH:30][C:25]([CH2:24][O:23][C:22]2[CH:21]=[CH:20][C:19]([CH2:18][S:15][C:12]3[CH:13]=[CH:14][C:6]([O:5][CH2:4][C:3]([OH:2])=[O:16])=[C:7]4[C:11]=3[CH2:10][CH2:9][CH2:8]4)=[CH:37][CH:36]=2)=[CH:26][C:27]=1[C:32]([F:33])([F:34])[F:35]