1-(Bromomethyl)-4-(trifluoromethoxy)benzene → HCID 22280124, compound
Reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][C:10]([F:13])([F:12])[F:11])=[CH:5][CH:4]=1.C[O:15][C:16](=[O:37])[CH2:17][O:18][C:19]1[CH:27]=[CH:26][C:25]([S:28][CH2:29][C:30]2[CH:35]=[CH:34][C:33]([OH:36])=[CH:32][CH:31]=2)=[C:24]2[C:20]=1[CH2:21][CH2:22][CH2:23]2>>[F:11][C:10]([F:13])([F:12])[O:9][C:6]1[CH:7]=[CH:8][C:3]([CH2:2][O:36][C:33]2[CH:32]=[CH:31][C:30]([CH2:29][S:28][C:25]3[CH:26]=[CH:27][C:19]([O:18][CH2:17][C:16]([OH:37])=[O:15])=[C:20]4[C:24]=3[CH2:23][CH2:22][CH2:21]4)=[CH:35][CH:34]=2)=[CH:4][CH:5]=1Participants
3
Procedure
The title compound was prepared in the manner analogous to Example 1F using 1-bromomethyl-4-trifluoromethoxy-benzene and 75C. MS m/z 519 (M+1).
Sources & evidence
- ORD record
- ord-c2f879c516ee49f085d65c7d7ff80aaa
- Source dataset
- uspto-grants-2005_11
- Patent number
- US06964983B2
Reaction notes
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