HCID 20827096, compound → HCID 22280077, compound

HRID 1063736Notes

Reaction equation

HRID 1063736 reaction equation
COC1C=CC(CO)=CC=1OCC1C=CC(C(F)(F)F)=CC=1.C[O:24][C:25](=[O:59])[CH2:26][O:27][C:28]1[CH:36]=[CH:35][C:34]([S:37][CH2:38][C:39]2[CH:44]=[CH:43][C:42]([O:45][CH3:46])=[C:41]([O:47][CH2:48][C:49]3[CH:54]=[CH:53][C:52]([C:55]([F:58])([F:57])[F:56])=[CH:51][CH:50]=3)[CH:40]=2)=[C:33]2[C:29]=1[CH2:30][CH2:31][CH2:32]2>>[CH3:46][O:45][C:42]1[CH:43]=[CH:44][C:39]([CH2:38][S:37][C:34]2[CH:35]=[CH:36][C:28]([O:27][CH2:26][C:25]([OH:59])=[O:24])=[C:29]3[C:33]=2[CH2:32][CH2:31][CH2:30]3)=[CH:40][C:41]=1[O:47][CH2:48][C:49]1[CH:54]=[CH:53][C:52]([C:55]([F:58])([F:56])[F:57])=[CH:51][CH:50]=1

Participants

3

Reactant 2

HCID 20827096HCID 20827096, compound2×HCID 22280080HCID 22280080, compound

Product 1

HCID 22280077HCID 22280077, compound

Procedure

The title compound was prepared in the manner analogous to Example 3B using 78A. MS m/z 295 (M-Cl). Step 3. Preparation of {7-[4-Methoxy-3-(4-trifluoromethyl-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acid methyl ester (Compound 78C)

Sources & evidence

ORD record
ord-88bc25e4a86d4bb7957f3bd2e419210b
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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