(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl Ester → HCID 22280077, compound

HRID 1063737Notes

Reaction equation

HRID 1063737 reaction equation
Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH3:10])=[C:5]([O:11][CH2:12][C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][CH:14]=2)[CH:4]=1.C[O:24][C:25](=[O:38])[CH2:26][O:27][C:28]1[CH:36]=[CH:35][C:34]([SH:37])=[C:33]2[C:29]=1[CH2:30][CH2:31][CH2:32]2>>[CH3:10][O:9][C:6]1[CH:7]=[CH:8][C:3]([CH2:2][S:37][C:34]2[CH:35]=[CH:36][C:28]([O:27][CH2:26][C:25]([OH:38])=[O:24])=[C:29]3[C:33]=2[CH2:32][CH2:31][CH2:30]3)=[CH:4][C:5]=1[O:11][CH2:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 20770872(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl EsterHCID 222800124-Chloromethyl-1-methoxy-2-(4-trifluoromethyl-benzyloxy)-benzene

Product 1

HCID 22280077HCID 22280077, compound

Procedure

The title compound was prepared in the manner analogous to Example 1F using 78B and 12C. MS m/z 373 (M−159).

Sources & evidence

ORD record
ord-f1e4252ff6da477e92f77f5a8fd59afd
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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