{7-[3-(4-Trifluoromethyl-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acid methyl ester → HCID 22280149, compound

HRID 1063739Notes

Reaction equation

HRID 1063739 reaction equation
FC(F)(F)C1C=CC(COC2C=C(CO)C=CC=2)=CC=1.C[O:22][C:23](=[O:55])[CH2:24][O:25][C:26]1[CH:34]=[CH:33][C:32]([S:35][CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH2:44][C:45]3[CH:50]=[CH:49][C:48]([C:51]([F:54])([F:53])[F:52])=[CH:47][CH:46]=3)[CH:38]=2)=[C:31]2[C:27]=1[CH2:28][CH2:29][CH2:30]2>>[F:53][C:51]([F:52])([F:54])[C:48]1[CH:49]=[CH:50][C:45]([CH2:44][O:43][C:39]2[CH:38]=[C:37]([CH:42]=[CH:41][CH:40]=2)[CH2:36][S:35][C:32]2[CH:33]=[CH:34][C:26]([O:25][CH2:24][C:23]([OH:55])=[O:22])=[C:27]3[C:31]=2[CH2:30][CH2:29][CH2:28]3)=[CH:46][CH:47]=1

Participants

3

Reactant 2

HCID 20827074{7-[3-(4-Trifluoromethyl-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acid methyl ester2×HCID 22280195[3-(4-Trifluoromethyl-benzyloxy)-phenyl]-methanol

Product 1

HCID 22280149HCID 22280149, compound

Procedure

The title compound was prepared in the manner analogous to Example 3B using 79A. MS m/z 265 (M-Cl). Step 3. Preparation of {7-[3-(4-Trifluoromethyl-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic acid methyl ester (Compound 79C)

Sources & evidence

ORD record
ord-9135c946ae6947eaa0ab868a36818b86
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

Loading…