Potassium Bromide → HCID 22280178, compound

Participants

Role	Name	HCID	Charge
Reactant	Potassium Bromide	HCID 253877	—
Reactant	{7-[2-(4-Trifluoromethyl-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic Acid Methyl Ester	HCID 20827069	—
Product	HCID 22280178	HCID 22280178	—

Reaction Steps

The title compound was prepared in the manner analogous to Example 1 using 81C. mp 150-152° C.; IR (KBr) cm−1: 3074, 3042, 1701, 1324, 1124, 1099; 400 MHz 1H NMR (DMSO-d6): δ 7.58-7.75 (m, 2H), 6.92-7.20 (m, 4H), 6.80 (t, 1H, J=7.5 Hz), 6.51 (d, 1H, J=8.5 Hz), 5.16 (s, 2H), 4.57 (s, 2H), 3.99 (s, 2H), 2.70 (t, 2H, J=7.5 Hz), 2.62 (t, 2H, J=7.5 Hz), 1.80 (pentet, 2H); MS m/z 487 (M−1). Anal. Calc'd for C26H23F3O4S: C, 63.92; H, 4.75. found: C, 63.54; H, 4.52.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06964983B2
Source dataset	uspto-grants-2005_11
ORD ID	ord-9f63142487fa4a6cad4895e115469997
Source note	uspto-grants-2005_11