(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl Ester → HCID 22280055, compound

HRID 1063757Notes

Reaction equation

HRID 1063757 reaction equation
C[O:2][C:3](=[O:16])[CH2:4][O:5][C:6]1[CH:14]=[CH:13][C:12]([SH:15])=[C:11]2[C:7]=1[CH2:8][CH2:9][CH2:10]2.Br[CH2:18][CH2:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]2[CH:31]=[CH:30][C:29]([C:32]([F:35])([F:34])[F:33])=[CH:28][CH:27]=2)=[CH:22][CH:21]=1>>[F:33][C:32]([F:34])([F:35])[C:29]1[CH:28]=[CH:27][C:26]([C:23]2[CH:24]=[CH:25][C:20]([CH2:19][CH2:18][S:15][C:12]3[CH:13]=[CH:14][C:6]([O:5][CH2:4][C:3]([OH:2])=[O:16])=[C:7]4[C:11]=3[CH2:10][CH2:9][CH2:8]4)=[CH:21][CH:22]=2)=[CH:31][CH:30]=1

Participants

3

Reactant 2

HCID 20770872(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl EsterHCID 22280025HCID 22280025, compound2×

Product 1

HCID 22280055HCID 22280055, compound

Procedure

The title compound was prepared in the manner analogous to Example 1F using 12C and 4-(2-bromo-ethyl)-4′-trifluoromethyl-biphenyl (Compound 22B). MS m/z 487 (M+1).

Sources & evidence

ORD record
ord-9ad5451663e9444280a33687673ed268
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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