HuagongsheHuagongshe Chemistry Print Report · For research reference only
(8-Mercapto-chroman-5-yloxy)-acetic acid methyl ester → {8-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-5-yloxy}-acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (8-Mercapto-chroman-5-yloxy)-acetic acid methyl ester | HCID 11288267 | — |
| Reactant | 3-(Chloromethyl)-5-[4-(trifluoromethyl)phenyl]isoxazole | HCID 22064260 | — |
| Product | {8-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-5-yloxy}-acetic Acid | HCID 22280091 | — |
Reaction Steps
The title compound was prepared in the manner analogous to Example 1F using 42C and (8-mercapto-chroman-5-yloxy)-acetic acid methyl ester. mp 112-113° C.; MS m/z 480 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06964983B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-1c801abf11e14c2db47536224dd4dc41 |
| Source note | uspto-grants-2005_11 |