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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063760Generated: November 2, 2026

3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazole → {4-[5-(4-Chloro-phenyl)-isoxazol-3-ylmethylsulfanyl]-2-methyl-phenoxy}-acetic Acid

https://huagongshe.com/reaction/1063760

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazoleHCID 1481100—
ReactantMethyl (2-methyl-4-sulfanylphenoxy)acetateHCID 20770797—
Product{4-[5-(4-Chloro-phenyl)-isoxazol-3-ylmethylsulfanyl]-2-methyl-phenoxy}-acetic AcidHCID 22280198—

Reaction Steps

The title compound was prepared in the manner analogous to Example 1F using 3-chloromethyl-5-(4-chloro-phenyl)-isoxazole and 2C. mp 79-80° C.; MS m/z 404 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-170439d54b2a4ee89197c31115d71d20
Source noteuspto-grants-2005_11