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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063761Generated: November 3, 2026

3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazole → {7-[5-(4-Chloro-phenyl)-isoxazol-3-ylmethylsulfanyl]-indan-4-yloxy}-acetic Acid

https://huagongshe.com/reaction/1063761

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazoleHCID 1481100—
Reactant(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl EsterHCID 20770872—
Product{7-[5-(4-Chloro-phenyl)-isoxazol-3-ylmethylsulfanyl]-indan-4-yloxy}-acetic AcidHCID 22280027—

Reaction Steps

The title compound was prepared in the manner analogous to Example 1F using 3-chloromethyl-5-(4-chloro-phenyl)-isoxazole and 12C. mp 112-114° C.; MS m/z 430 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-8cad9c38b5ee401f92a0c76eb6d813e4
Source noteuspto-grants-2005_11