5-(Chloromethyl)-3-(4-chlorophenyl)-1,2-oxazole → HCID 22280033, compound

HRID 1063762Notes

Reaction equation

HRID 1063762 reaction equation
Cl[CH2:2][C:3]1[O:7][N:6]=[C:5]([C:8]2[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][CH:9]=2)[CH:4]=1.C[O:16][C:17](=[O:30])[CH2:18][O:19][C:20]1[CH:28]=[CH:27][C:26]([SH:29])=[C:25]2[C:21]=1[CH2:22][CH2:23][CH2:24]2>>[Cl:14][C:11]1[CH:12]=[CH:13][C:8]([C:5]2[CH:4]=[C:3]([CH2:2][S:29][C:26]3[CH:27]=[CH:28][C:20]([O:19][CH2:18][C:17]([OH:30])=[O:16])=[C:21]4[C:25]=3[CH2:24][CH2:23][CH2:22]4)[O:7][N:6]=2)=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 27640565-(Chloromethyl)-3-(4-chlorophenyl)-1,2-oxazoleHCID 20770872(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl Ester

Product 1

HCID 22280033HCID 22280033, compound

Procedure

The title compound was prepared in the manner analogous to Example 1F using 5-chloromethyl-3-(4-chloro-phenyl)-isoxazole and 12C. mp 92-94° C.; MS m/z 430 (M+1).

Sources & evidence

ORD record
ord-c70f7c2ed2554278909ff408def049fe
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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