tert-Butyl piperazine-1-carboxylate → HCID 22277287, compound

HRID 1063858Notes

Reaction equation

HRID 1063858 reaction equation
[Cl:1][C:2]1[C:7]2[CH:8]=[CH:9][O:10][C:6]=2[C:5](Br)=[CH:4][C:3]=1[C:12]([O:14][CH3:15])=[O:13].C([O:20][C:21]([N:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1)=[O:22])(C)(C)C>>[C:12]([OH:14])(=[O:13])[C:21]([OH:20])=[O:22].[Cl:1][C:2]1[C:7]2[CH:8]=[CH:9][O:10][C:6]=2[C:5]([N:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)=[CH:4][C:3]=1[C:12]([O:14][CH3:15])=[O:13]

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 22144735HCID 22144735, compound

Product 1

HCID 22277287HCID 22277287, compound

Procedure

Beginning with 4-chloro-5-methoxycarbonyl-7-bromobenzofuran and 1-tert-butoxycarbonylpiperazine, the title compound was prepared as described.

Sources & evidence

ORD record
ord-9676c1e6f82e497885dc2c5d457c9219
Source dataset
uspto-grants-2005_11
Patent number
US06967201B1

Reaction notes

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