(S)-1-Benzyl-3-methylpiperazine → 1-(5-chlorobenzofur-7-yl)-2(S)-methylpiperazine Hydrochloride

HRID 1063860Notes

Reaction equation

HRID 1063860 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4](Br)[C:5]2[O:9][CH:8]=[CH:7][C:6]=2[CH:10]=1.C([N:19]1[CH2:24][CH2:23][NH:22][C@@H:21]([CH3:25])[CH2:20]1)C1C=CC=CC=1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([N:22]2[CH2:23][CH2:24][NH:19][CH2:20][C@@H:21]2[CH3:25])[C:5]2[O:9][CH:8]=[CH:7][C:6]=2[CH:10]=1

Participants

3

Reactant 2

HCID 6923224(S)-1-Benzyl-3-methylpiperazineHCID 221447207-Bromo-5-chloro-1-benzofuran

Product 1

HCID 234023941-(5-chlorobenzofur-7-yl)-2(S)-methylpiperazine Hydrochloride

Procedure

Beginning with 5-chloro-7-bromobenzofuran and 1-benzyl-3(S)-methylpiperazine, the title compound was prepared as described.

Sources & evidence

ORD record
ord-c897b3d83a15450caca4c8f927531217
Source dataset
uspto-grants-2005_11
Patent number
US06967201B1

Reaction notes

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