tert-Butyl piperazine-1-carboxylate → HCID 22277268, compound

HRID 1063861Notes

Reaction equation

HRID 1063861 reaction equation
[F:1][C:2]1[C:3]([Cl:12])=[C:4](Br)[C:5]2[O:9][CH:8]=[CH:7][C:6]=2[CH:10]=1.C(OC([N:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1)=O)(C)(C)C>>[ClH:12].[F:1][C:2]1[C:3]([Cl:12])=[C:4]([N:20]2[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]2)[C:5]2[O:9][CH:8]=[CH:7][C:6]=2[CH:10]=1

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 22277281HCID 22277281, compound

Product 1

HCID 22277268HCID 22277268, compound

Procedure

Beginning with 0.26 gm (1.06 mMol) 5-fluoro-6-chloro-7-bromobenzofuran and 0.22 gm (1.16 mMol) 1-tert-butoxycarbonylpiperazine, the title compound was prepared essentially as described in GENERAL PROCEDURE II.

Sources & evidence

ORD record
ord-0d513cf1ba95443a9784f970e3279290
Source dataset
uspto-grants-2005_11
Patent number
US06967201B1

Reaction notes

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