2-Methylpiperazine, (R)- → HCID 23402360, compound

HRID 1063867Notes

Reaction equation

HRID 1063867 reaction equation
[Cl:1][C:2]1[C:7]2[CH:8]=[CH:9][O:10][C:6]=2[C:5](Br)=[C:4]([Cl:12])[CH:3]=1.[CH3:13][C@@H:14]1[CH2:19][NH:18][CH2:17][CH2:16][NH:15]1>>[ClH:1].[Cl:1][C:2]1[C:7]2[CH:8]=[CH:9][O:10][C:6]=2[C:5]([N:18]2[CH2:17][CH2:16][NH:15][C@H:14]([CH3:13])[CH2:19]2)=[C:4]([Cl:12])[CH:3]=1

Participants

3

Reactant 2

HCID 73304342-Methylpiperazine, (R)-HCID 22144862HCID 22144862, compound

Product 1

HCID 23402360HCID 23402360, compound

Procedure

Beginning with 0.31 gm (1.2 mmol) 4,6-dichloro-7-bromobenzofuran and 0.12 gm (1.2 mMol) 2(R)-methylpiperazine, the title compound was prepared essentially as described in GENERAL PROCEDURE IV.

Sources & evidence

ORD record
ord-317595a39e9744e1869a232a8180c7dd
Source dataset
uspto-grants-2005_11
Patent number
US06967201B1

Reaction notes

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