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HRID1063955

反应详情

EQUATION

反应方程式

HRID 1063955 的结构方程式

REACTANTS

反应物

3
结构：ClP(Cl)(Cl)(Cl)Cl
HCID24819

Phosphorus pentachloride

Cl5P

结构：CCCCCS(=O)(=O)Cl
HCID237555

1-Pentanesulfonyl chloride

C5H11ClO2S

结构：C[C@H](CCCS(=O)(=O)O)N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1
HCID54303834

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](CCCS(=O)(=O)Cl)N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1
HCID53996712

未命名化合物

收率 88%

PROCEDURE

实验过程

(4R)-4-[N-[2,5-difluorophenyl][(4-chlorophenyl)sulfonyl]amino]pentylsulfonyl chloride was prepared analogous to (4R)-4-[2,5-dichlorophenyl][4-chlorophenyl)sulfonyl]-amino]pentylsulfonyl chloride by reacting (4R)-4-[N-[2,5-difluorophenyl][(4-chlorophenyl)sulfonyl]amino]pentylsulfonic acid with phosphorus pentachloride. Yield=88%; MS (ESI) 434 (M+1).