HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Thiophenamine, tetrahydro-, 1,1-dioxide → Benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Thiophenamine, tetrahydro-, 1,1-dioxide | HCID 22807 | — |
| Reactant | 1-Pentanesulfonyl chloride | HCID 237555 | — |
| Reactant | HCID 53796417 | HCID 53796417 | — |
| Product | Benzenesulfonamide | HCID 7370 | 23% |
Reaction Steps
4-chloro-N-[2,5-dichlorophenyl]-N-[4-[[(tetrahydro-], 1-dioxido-3-thienyl)amino]sulfonyl]-1(R)-methylbutyl]benzenesulfonamide was prepared analogous to 4-chloro-N-[2,5-dichlorophenyl]-N-[4[(methylamino)sulfonyl]-1(R)-methylbutyl]benzenesulfonamide by reacting (4R)-4-[2,5-dichlorophenyl][4-chlorophenyl)sulfonyl]-amino]pentylsulfonyl chloride with tetrahydro-1,1-dioxido-3-thienylamine. Yield=23%; MS (ESI+), 603 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06967196B1 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-d1c3389b21e249d4913522fb225b649d |
| Source note | uspto-grants-2005_11 |