1,1-Dichloroethane → 3-Bromo-4-[(2,4-difluorobenzyl)oxy]-1-(2,6-difluorophenyl)-5-iodo-6-methylpyridin-2(1H)-one

HRID 106401Notes

Reaction equation

HRID 106401 reaction equation
[Br:1][c:2]1[c:3](=[O:27])[n:4](-[c:19]2[c:20]([F:26])[cH:21][cH:22][cH:23][c:24]2[F:25])[c:5]([CH3:18])[cH:6][c:7]1[O:8][CH2:9][c:10]1[c:11]([F:17])[cH:12][c:13]([F:16])[cH:14][cH:15]1.[Cl:42][CH:43]([Cl:44])[CH3:45].[I:28][N:29]1[C:30](=[O:31])[CH2:32][CH2:33][C:34]1=[O:35].[OH:36][C:37]([CH:38]([Cl:39])[Cl:40])=[O:41]>>[Br:1][c:2]1[c:3](=[O:27])[n:4](-[c:19]2[c:20]([F:26])[cH:21][cH:22][cH:23][c:24]2[F:25])[c:5]([CH3:18])[c:6]([I:28])[c:7]1[O:8][CH2:9][c:10]1[c:11]([F:17])[cH:12][c:13]([F:16])[cH:14][cH:15]1

Participants

5

Reactant 4

HCID 63651,1-DichloroethaneHCID 6597Dichloroacetic AcidHCID 120273N-IodosuccinimideHCID 220501433-Bromo-4-[(2,4-difluorobenzyl)oxy]-1-(2,6-difluorophenyl)-6-methylpyridin-2(1H)-one

Product 1

HCID 220499923-Bromo-4-[(2,4-difluorobenzyl)oxy]-1-(2,6-difluorophenyl)-5-iodo-6-methylpyridin-2(1H)-one

Sources & evidence

ORD record
ord-ea4d9e183e97453c93753443dc25b484
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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