Methanol → HCID 69356330, compound

Participants

Reaction Conditions

Reaction Steps

The solution of 2-(4-Chloro-phenyl)-3-pyridin-4-yl-acrylic acid 3.5 g in thionyl chloride 25 mL was heated to 70° C. for five hours. The reaction was cooled to 0° C., then was added methanol 50 mL. After warm to room temperature over one hour, all the solvent removed under reduced pressure. Work up using ethyl acetate and sodium bicarbonate give the light yellow solid. MS (ES+): 274 (M+H)+.

Provenance & Evidence