HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-pyrazolidin-3-one → 4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-1,2-dihydro-pyrazol-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-pyrazolidin-3-one | HCID 22277994 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-1,2-dihydro-pyrazol-3-one | HCID 10267120 | — |
Reaction Steps
The solution of 4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-pyrazolidin-3-one 0.30 g, 20 mg Pd/C and 20 mL methanol was stirred at room temperature. Air was bubbled through for 2 hours. Filtered off the Pd/C catalyst, vacuumed down all solvent. The title compound was obtained as white solid 0.29 g. MS (ES+): 306 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06967254B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-e2745fa2c552426ba70f5438b53e9be8 |
| Source note | uspto-grants-2005_11 |