N-[3-bromo-5-(pyridine-3-carbonyl)-phenyl]-propionamide → N-[3-(1H-indol-4-yl)-5-(pyridine-3-carbonyl)-phenyl]-propionamide

HRID 106432Notes

Reaction equation

HRID 106432 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:5][C:6](=[O:7])[CH2:8][CH3:9])[cH:10][c:11]([C:12]([c:13]2[cH:14][n:15][cH:16][cH:17][cH:18]2)=[O:19])[cH:20]1.[n:21]1[cH:22][c:23]([C:27](=[O:28])[c:29]2[cH:30][c:31]([NH:54][C:55]([CH2:56][CH3:57])=[O:58])[cH:32][c:33](-[c:35]3[c:36]4[cH:37][cH:38][n:39]([Si:44]([CH:45]([CH3:46])[CH3:47])([CH:48]([CH3:49])[CH3:50])[CH:51]([CH3:52])[CH3:53])[c:40]4[cH:41][cH:42][cH:43]3)[cH:34]2)[cH:24][cH:25][cH:26]1>>[n:21]1[cH:22][c:23]([C:27](=[O:28])[c:29]2[cH:30][c:31]([NH:54][C:55]([CH2:56][CH3:57])=[O:58])[cH:32][c:33](-[c:35]3[c:36]4[cH:37][cH:38][nH:39][c:40]4[cH:41][cH:42][cH:43]3)[cH:34]2)[cH:24][cH:25][cH:26]1

Participants

3

Reactant 2

HCID 68844539N-[3-bromo-5-(pyridine-3-carbonyl)-phenyl]-propionamideHCID 68846779N-[3-(pyridine-3-carbonyl)-5-(1-triisopropylsilanyl-1H-indol-4-yl)-phenyl]-propionamide

Product 1

HCID 15602990N-[3-(1H-indol-4-yl)-5-(pyridine-3-carbonyl)-phenyl]-propionamide

Sources & evidence

ORD record
ord-c3073b9b01704c168ac5b64ef1aed3a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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