4-(3-Dimethylaminoprop-2-en-1-oyl)-1-triphenylmethylimidazole → 2-(3-Chloroanilino)-4-(1-triphenylmethylimidazol-4-yl)pyrimidine

HRID 1064323Notes

Reaction equation

HRID 1064323 reaction equation
CN(C)[CH:3]=[CH:4][C:5]([C:7]1[N:8]=[CH:9][N:10]([C:12]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:11]=1)=O.[Cl:32][C:33]1[CH:34]=[C:35]([NH:39][C:40]([NH2:42])=[NH:41])[CH:36]=[CH:37][CH:38]=1>>[Cl:32][C:33]1[CH:34]=[C:35]([CH:36]=[CH:37][CH:38]=1)[NH:39][C:40]1[N:42]=[C:5]([C:7]2[N:8]=[CH:9][N:10]([C:12]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:11]=2)[CH:4]=[CH:3][N:41]=1

Participants

3

Reactant 2

HCID 696659324-(3-Dimethylaminoprop-2-en-1-oyl)-1-triphenylmethylimidazoleHCID 178512488HCID 178512488, compound

Product 1

HCID 222735042-(3-Chloroanilino)-4-(1-triphenylmethylimidazol-4-yl)pyrimidine

Procedure

4-(3-Dimethylaminoprop-2-en-1-oyl)-1-triphenylmethylimidazole (Method 3) was treated with 3-chlorophenylguanidine under conditions analogous to those described in Example 7 to give the title compound; m/z: 514.

Sources & evidence

ORD record
ord-189d70e2234145709c678f9459c11a27
Source dataset
uspto-grants-2005_11
Patent number
US06969714B2

Reaction notes

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