Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 4-chloro-N-(2-methoxyphenyl)-3-nitrobenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 2-Methoxyaniline | HCID 7000 | — |
| 반응물 | 4-Chloro-3-nitrobenzenesulfonamide | HCID 7324 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 4-chloro-N-(2-methoxyphenyl)-3-nitrobenzenesulfonamide | HCID 2887683 | — |
반응 단계
4-Chloro-3-nitrobenzenesulfonamide (1.73 g, 6.78 mmol) was dissolved in CH2Cl2 (7.0 mL). o-Anisidine (1.00 g, 8.13 mmol) was added dropwise at room temperature, followed by a slow addition of pyridine (2.0 mL). After 16 h of continued stirring, the reaction mixture was diluted with EtOAc (50 mL) and washed with 1 M HCl (3×50 mL).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06969710B2 |
| 출처 데이터셋 | uspto-grants-2005_11 |
| ORD ID | ord-89a9e338246d4eeda76c9350ae94dcc3 |
| 출처 메모 | uspto-grants-2005_11 |