2-Chloro-N-(quinolin-5-yl)acetamide → HCID 22273408, compound

HRID 1064574Notes

Reaction equation

HRID 1064574 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9](=[O:29])[CH2:10][N:11]1[CH2:17][CH:16]2[N:18]([C:19]3[N:27]=[CH:26][N:25]=[C:24]4[C:20]=3[N:21]=[CH:22][N:23]4[CH3:28])[CH:13]([CH2:14][CH2:15]2)[CH2:12]1.Cl[CH2:31][C:32]([NH:34]C1C=CC=C2C=1C=CC=N2)=O>>[CH3:28][N:23]1[CH:22]=[N:21][C:20]2[C:24]1=[N:25][CH:26]=[N:27][C:19]=2[N:18]1[CH:16]2[CH2:15][CH2:14][CH:13]1[CH2:12][N:11]([CH2:10][C:9]([NH:8][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]3[C:2]=1[CH:1]=[CH:31][CH:32]=[N:34]3)=[O:29])[CH2:17]2

Participants

3

Reactant 2

HCID 8560192-Chloro-N-(quinolin-5-yl)acetamideHCID 10178546HCID 10178546, compound

Product 1

HCID 22273408HCID 22273408, compound

Procedure

The subtitle compound was prepared from the product of Example 20 step (ii) (0.24 g) and 2-chloro-N-(quinolin-5-yl)acetamide (J. Indian Chem. Soc, 1940, 17, 619-621) (0.234 g) by the method of Example 20 step (iii) as a pale yellow solid. Yield 0.38 g.

Sources & evidence

ORD record
ord-5c34c4026e9c493dbe40bdd79e183b73
Source dataset
uspto-grants-2005_11
Patent number
US06969713B2

Reaction notes

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