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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064577Generated: October 31, 2026

Chloroacetyl chloride → 2-Chloro-N-(2-oxo-2,3-dihydro-1H-indol-4-yl)acetamide

https://huagongshe.com/reaction/1064577

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetyl chlorideHCID 6577—
Reactant4-Aminoindolin-2-oneHCID 12237472—
Product2-Chloro-N-(2-oxo-2,3-dihydro-1H-indol-4-yl)acetamideHCID 22273397—

Reaction Steps

The subtitle compound was prepared from 4-amino-oxindole (0.19 g) (J. Org. Chem., 1983, 48 (15), 2468-72) and chloroacetyl chloride (0.1 ml) by the method of Example 15 step (i). Yield: 0.25 g

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06969713B2
Source datasetuspto-grants-2005_11
ORD IDord-20a32be6b28042559c15607bb7bff461
Source noteuspto-grants-2005_11