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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064594Generated: November 1, 2026

Chloroacetyl chloride → 2-Chloro-N-[2-(trifluoromethyl)phenyl]acetamide

https://huagongshe.com/reaction/1064594

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetyl chlorideHCID 6577—
Reactant2-(Trifluoromethyl)anilineHCID 6922—
Product2-Chloro-N-[2-(trifluoromethyl)phenyl]acetamideHCID 737278—

Reaction Steps

The subtitle compound was prepared from 2-trifluoromethylaniline(10.5 g) and chloroacetyl chloride (6.8 ml) by the method of Example 33 step (iii) as a white solid. Yield: 13.7 g

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06969713B2
Source datasetuspto-grants-2005_11
ORD IDord-16e22f4069c6428a87bd5dd4cc422529
Source noteuspto-grants-2005_11