3-Cyanobenzene-1-sulfonyl chloride → HCID 69744923, compound

HRID 1064595Notes

Reaction equation

HRID 1064595 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9](=[O:19])[CH2:10][N:11]1[CH2:16][C@H:15]([CH3:17])[NH:14][C@H:13]([CH3:18])[CH2:12]1.[C:20]([C:22]1[CH:23]=[C:24]([S:28](Cl)(=[O:30])=[O:29])[CH:25]=[CH:26][CH:27]=1)#[N:21]>>[C:20]([C:22]1[CH:23]=[C:24]([S:28]([N:14]2[C@@H:13]([CH3:18])[CH2:12][N:11]([CH2:10][C:9]([NH:8][C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])=[O:19])[CH2:16][C@H:15]2[CH3:17])(=[O:30])=[O:29])[CH:25]=[CH:26][CH:27]=1)#[N:21]

Participants

3

Reactant 2

HCID 28013603-Cyanobenzene-1-sulfonyl chlorideHCID 69746814HCID 69746814, compound

Product 1

HCID 69744923HCID 69744923, compound

Procedure

The title compound was prepared from the product of Example 15 step (ii) (0.2 g) and 3-cyanobenzenesulphonyl chloride (0.28 g) by the method of Example 74 as a white solid. Yield 8 mg.

Sources & evidence

ORD record
ord-375b9b9f2a294a169c8b589ce34710ad
Source dataset
uspto-grants-2005_11
Patent number
US06969713B2

Reaction notes

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