3-Cyanobenzene-1-sulfonyl chloride → HCID 69745116, compound

HRID 1064598Notes

Reaction equation

HRID 1064598 reaction equation
[CH3:1][C@H:2]1[NH:7][C@@H:6]([CH3:8])[CH2:5][N:4]([CH2:9][C:10]([NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[C:14]=2[CH3:21])=[O:11])[CH2:3]1.[C:22]([C:24]1[CH:25]=[C:26]([S:30](Cl)(=[O:32])=[O:31])[CH:27]=[CH:28][CH:29]=1)#[N:23]>>[C:22]([C:24]1[CH:25]=[C:26]([S:30]([N:7]2[C@@H:6]([CH3:8])[CH2:5][N:4]([CH2:9][C:10]([NH:12][C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[C:14]=3[CH3:21])=[O:11])[CH2:3][C@H:2]2[CH3:1])(=[O:32])=[O:31])[CH:27]=[CH:28][CH:29]=1)#[N:23]

Participants

3

Reactant 2

HCID 28013603-Cyanobenzene-1-sulfonyl chlorideHCID 69745130HCID 69745130, compound

Product 1

HCID 69745116HCID 69745116, compound

Procedure

The title compound was prepared from the product of Example 65 step (i) (0.503 mmol) and 3-cyanobenzenesulphonyl chloride (0.503 mmol) by the method of Example 58 step (ii) as a white solid. Yield: 21 mg

Sources & evidence

ORD record
ord-43d38ac64ba34b2797eb388bdafefb42
Source dataset
uspto-grants-2005_11
Patent number
US06969713B2

Reaction notes

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