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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064599Generated: October 31, 2026

Chloroacetyl chloride → 2-chloro-N-(5-cyano-2-methylphenyl)acetamide

https://huagongshe.com/reaction/1064599

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetyl chlorideHCID 6577—
Reactant3-Amino-4-methylbenzonitrileHCID 7016428—
Product2-chloro-N-(5-cyano-2-methylphenyl)acetamideHCID 22273411—

Reaction Steps

The subtitle compound was prepared from 5-cyano-2-methylaniline (1.6 g) and chloroacetyl chloride (1.1 ml) by the method of Example 33 step (iii) as a white solid. Yield: 1.85 g

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06969713B2
Source datasetuspto-grants-2005_11
ORD IDord-d0b2a27f980f44f9a915d37d1c4e497c
Source noteuspto-grants-2005_11