2-Chloro-N-(quinolin-5-yl)acetamide → HCID 69744758, compound

HRID 1064603Notes

Reaction equation

HRID 1064603 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:7]=1[CH:8]=[CH:9][CH:10]=[N:11]2)=[O:4].[CH3:16][C@H:17]1[CH2:22][NH:21][CH2:20][CH2:19][NH:18]1>>[CH3:16][C@@H:17]1[NH:18][CH2:19][CH2:20][N:21]([CH2:2][C:3]([NH:5][C:6]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:7]=2[CH:8]=[CH:9][CH:10]=[N:11]3)=[O:4])[CH2:22]1

Participants

3

Reactant 2

HCID 8560192-Chloro-N-(quinolin-5-yl)acetamideHCID 27342192-Methylpiperazine, (S)-

Product 1

HCID 69744758HCID 69744758, compound

Procedure

to The subtitle compound was prepared from 2-chloro-N-(quinolin-5-yl)acetamide (1 g) (J Indian Chem Soc, 1940, 17, 619-621) and (S)-2-methylpiperazine (0.5 g) by the method of Example 58 step (i) as a white solid. Yield: 1.4 g

Sources & evidence

ORD record
ord-0fff0865963c4c87822de41460bd257e
Source dataset
uspto-grants-2005_11
Patent number
US06969713B2

Reaction notes

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