HCID 22273464, compound → cis-2-[4-(3-Cyanobenzenesulphonyl)-3,5-dimethylpiperazin-1-yl]-n-(2-methyl-5-methanesulphonylphenyl)acetamide

HRID 1064606Notes

Reaction equation

HRID 1064606 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[C:10]([S:12]([CH3:15])(=[O:14])=[O:13])[CH:9]=[CH:8][C:7]=1[CH3:16])=[O:4].[C:17]([C:19]1[CH:20]=[C:21]([S:25]([N:28]2[C@H:33]([CH3:34])[CH2:32][NH:31][CH2:30][C@@H:29]2[CH3:35])(=[O:27])=[O:26])[CH:22]=[CH:23][CH:24]=1)#[N:18]>>[C:17]([C:19]1[CH:20]=[C:21]([S:25]([N:28]2[C@@H:33]([CH3:34])[CH2:32][N:31]([CH2:2][C:3]([NH:5][C:6]3[CH:11]=[C:10]([S:12]([CH3:15])(=[O:14])=[O:13])[CH:9]=[CH:8][C:7]=3[CH3:16])=[O:4])[CH2:30][C@H:29]2[CH3:35])(=[O:26])=[O:27])[CH:22]=[CH:23][CH:24]=1)#[N:18]

Participants

3

Reactant 2

HCID 22273464HCID 22273464, compoundHCID 69744750cis-1-(3-Cyanobenzenesulphonyl)-2,6-dimethylpiperazine

Product 1

HCID 69745609cis-2-[4-(3-Cyanobenzenesulphonyl)-3,5-dimethylpiperazin-1-yl]-n-(2-methyl-5-methanesulphonylphenyl)acetamide

Procedure

The title compound was prepared from the product of step (i) (0.14 g) and the product of Example 80 step (ii) by the method of Example 80 step (iii) as a white solid. Yield: 0.03 g

Sources & evidence

ORD record
ord-910fee9dcd374b83a9fdef769a011be2
Source dataset
uspto-grants-2005_11
Patent number
US06969713B2

Reaction notes

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