HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperidine → 4-{2-[2-(2-Methyl-1-piperidinyl)ethyl]-1-benzofuran-5-yl}benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperidine | HCID 7974 | — |
| Reactant | 2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl Methanesulfonate | HCID 11393678 | — |
| Product | 4-{2-[2-(2-Methyl-1-piperidinyl)ethyl]-1-benzofuran-5-yl}benzonitrile | HCID 10360149 | — |
Reaction Steps
The product from Example 1C and 2-methylpiperidine were processed as described in Example 1D to provide the titled compound. 1H NMR (300 MHz, CD3OD) δ 7.88 (m, 1H), 7.80 (m, 4H), 7.60 (m, 2H), 6.82 (s, 1H), 3.1-3.8 (m, 7H), 1.6-2.1 (m, 6H), 1.45 (d, 3H, J=6 Hz); MS (DCI) m/z 345 (M+H)+;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06969730B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-4ab02612e8924d5aaf839e36a41e0d8f |
| Source note | uspto-grants-2005_11 |