HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 4-(4-{2-[2-(1-Piperidinyl)ethyl]-1-benzofuran-5-yl}benzoyl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-{5-[4-(4-Morpholinylcarbonyl)phenyl]-1-benzofuran-2-yl}ethyl methanesulfonate | HCID 22274531 | — |
| Product | 4-(4-{2-[2-(1-Piperidinyl)ethyl]-1-benzofuran-5-yl}benzoyl)morpholine | HCID 10319869 | — |
Reaction Steps
The product from Example 23D and piperidine were processed as described in Example 1D to provide the titled compound. 1H NMR (300 MHz, CD3OD) δ 7.82 (m, 1H), 7.73 (d, J=8.1, 2H), 7.54 (m, 2H), 7.51 (d, J=8.1 Hz, 2H), 6.77(s, 1H), 3.32-3.8 (m, 14H), 3.07 (m, 2H), 1.5-2.1 (m, 6H); MS (DCI) m/z 419 (M+H)+;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06969730B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-f8d59a5de02f44d18902e79f9b62e438 |
| Source note | uspto-grants-2005_11 |