HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-Methylpyrrolidine → 4-{[6-(2-{2-[(2R)-methylpyrrolidinyl]ethyl}-1-benzofuran-5-yl)-3-pyridinyl]carbonyl}morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-Methylpyrrolidine | HCID 641544 | — |
| Reactant | 2-{5-[5-(4-Morpholinylcarbonyl)-2-pyridinyl]-1-benzofuran-2-yl}ethyl methanesulfonate | HCID 22274556 | — |
| Product | 4-{[6-(2-{2-[(2R)-methylpyrrolidinyl]ethyl}-1-benzofuran-5-yl)-3-pyridinyl]carbonyl}morpholine | HCID 44374493 | — |
Reaction Steps
The product from Example 44E and 2-(R)-methylpyrrolidine were processed as described in Example 1D to provide the titled compound. MS (DCI) m/z 420 (M+H)+;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06969730B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-50eb255ac28d454eaf9a6bdb3d6fc3ff |
| Source note | uspto-grants-2005_11 |