Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064704Generated: October 31, 2026

Dimethylamine → N,N-dimethyl-N-(2-{5-[5-(4-morpholinylcarbonyl)-2-pyridinyl]-1-benzofuran-2-yl}ethyl)amine

https://huagongshe.com/reaction/1064704

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant2-{5-[5-(4-Morpholinylcarbonyl)-2-pyridinyl]-1-benzofuran-2-yl}ethyl methanesulfonateHCID 22274556—
ProductN,N-dimethyl-N-(2-{5-[5-(4-morpholinylcarbonyl)-2-pyridinyl]-1-benzofuran-2-yl}ethyl)amineHCID 9969974—

Reaction Steps

The product from Example 44E and dimethylamine were processed as described in Example 1D to provide the titled compound. 1H NMR (300 MHz, CD3OD) δ8.70 (m, 1H), 8.24 (d, J=1.8 Hz, 1H), 7.96 (m, 3H), 7.59 (d, J=8.7 Hz, 1H), 6.84 (s, 1H), 3.35-3.8 (m, 12H), 2.98 (s, 6H); MS (DCI) m/z 380 (M+H)+;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06969730B2
Source datasetuspto-grants-2005_11
ORD IDord-6d4184d069a8494baedc34cd6e6ba0d2
Source noteuspto-grants-2005_11